Isotretinoin is a compound that is mostly used for treating severe cases of acne. The compound is also known as 13-cis-retinoic acid and is sold under many different brand names such as Roaccutane and many others. Nonetheless, Accutane brand remains the most popular one for Isotretinoin.
Except for being used to treat severe acne, the compound can be used for treating various other skin diseases and may be used for preventing or even treating certain skin cancers. Therefore, the studies done on Isotretinoin medication proved that it greatly deals with skin conditions and helps the skin faster renew itself.
Isotretinoin is a medication that can be found as oral pills or as a topical solution and this is actually a type of retinoid, which is known to be found in the body naturally, but in small amounts. Since it is a retinoid, it is associated with vitamin A.
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This medication has been patented in 1969 and then has been approved for use in medicine in 1982 when was proven very effective for dealing with acne. In the USA, the compound is given only via prescription as well as in many other countries. Nonetheless, Isotretinoin is still sold as an OTC drug in many countries.
Bodybuilders require Isotretinoin as an ancillary compound for anabolic steroids.
- Similar to how they run Aromatase Inhibitors (AIs) to deal with estrogen related issues during the cycle with steroids, they use Isotretinoin to deal with acne and skin issues during the cycle with steroids.
How Isotretinoin Works?
As earlier mentioned, Isotretinoin is a retinoid meaning that is associated with Vitamin A. Is working as an isomer of this vitamin. As a result, this is reducing the amount of oil that is being released by the oil glands in the skin. Since there’s much less oil – acne cannot grow and is actually significantly reduced.
Despite the fact that the exact mechanism of the action is not 100% known and can or be fully explained, it is known that Isotretinoin is working by inhibiting the function of the sebaceous glands. The development of acne is, therefore, reduced.
According to studies done on Isotretinoin, more than 90% of patients are reporting amazing results. And about 60% of the patients report their acne never recurred back after the use of Isotretinoin.
Isotretinoin in Bodybuilding
Bodybuilders running steroids are increasing testosterone and androgens. This is very likely to lead to acne, especially if they are genetically prone to get acne.
Is considered that in 80% of cases, acne is genetically occurring. Nonetheless, this condition may be associated with poor lifestyle choices such as smoking, poor diet, non active lifestyle, and many others.
Whilst bodybuilders are generally having a proper lifestyle, acne is mostly genetic and associated with the use of steroids. That’s similar to teenagers when they get a spike in testosterone and androgen levels and they are suffering from acne related issues.
Therefore, is the increase in the androgens that are going to trigger acne issues. And chances of this occurring are even higher in people who are genetically prone to get acne.
Isotretinoin Side Effects
Some of the most common Isotretinoin side effects are:
- Dry lips
- Dry and fragile skin
- Increased risks of sunburn
There are also rarer and uncommon side effects of Isotretinoin:
- Muscle pains
- Behavior changes
There are also very rare but serious side effects too:
- Visual changes
- And even suicidal thoughts
The list of Isotretinoin is much longer, but they are all very unlikely to appear to a bodybuilder who needs much lower doses than a person fighting off with severe acne.
- WARNING! Isotretinoin is very likely to cause developmental issues in the fetus even in very low dosages. Pregnant women shouldn’t use Isotretinoin.
Usually, Isotretinoin is given in doses of 50-150 mg a day to patients suffering from acne as a prescription drug by a doctor. Is usually recommended to use it with a large meal.
Nonetheless, bodybuilders who want to control acne during the cycle of steroids are generally using only 10-20 mg a day. Rarely in higher dosages. Usually, bodybuilders use it for 6-10 weeks.
But if the compound is prescribed by a doctor – use it exactly as was told by the doctor.
Keep in mind that the lower the dosage – the lower chances of side effects. Even if they do occur – lower chances usually mean milder side effects too. That’s why it is highly recommended to stay at the lowest effective dosage.
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