What Is Isotretinoin?


Isotretinoin is a compound that is mostly used for treating severe cases of acne. The compound is also known as 13-cis-retinoic acid and is sold under many different brand names such as Roaccutane and many others. Nonetheless, Accutane brand remains the most popular one for Isotretinoin.

Except for being used to treat severe acne, the compound can be used for treating various other skin diseases and may be used for preventing or even treating certain skin cancers. Therefore, the studies done on Isotretinoin medication proved that it greatly deals with skin conditions and helps the skin faster renew itself.

Isotretinoin is a medication that can be found as oral pills or as a topical solution and this is actually a type of retinoid, which is known to be found in the body naturally, but in small amounts. Since it is a retinoid, it is associated with vitamin A.


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This medication has been patented in 1969 and then has been approved for use in medicine in 1982 when was proven very effective for dealing with acne. In the USA, the compound is given only via prescription as well as in many other countries. Nonetheless, Isotretinoin is still sold as an OTC drug in many countries.

Bodybuilders require Isotretinoin as an ancillary compound for anabolic steroids.

  • Similar to how they run Aromatase Inhibitors (AIs) to deal with estrogen related issues during the cycle with steroids, they use Isotretinoin to deal with acne and skin issues during the cycle with steroids.

How Isotretinoin Works?

As earlier mentioned, Isotretinoin is a retinoid meaning that is associated with Vitamin A. Is working as an isomer of this vitamin. As a result, this is reducing the amount of oil that is being released by the oil glands in the skin. Since there’s much less oil – acne cannot grow and is actually significantly reduced.

Despite the fact that the exact mechanism of the action is not 100% known and can or be fully explained, it is known that Isotretinoin is working by inhibiting the function of the sebaceous glands. The development of acne is, therefore, reduced.

According to studies done on Isotretinoin, more than 90% of patients are reporting amazing results. And about 60% of the patients report their acne never recurred back after the use of Isotretinoin.


Isotretinoin in Bodybuilding

Bodybuilders running steroids are increasing testosterone and androgens. This is very likely to lead to acne, especially if they are genetically prone to get acne.

Is considered that in 80% of cases, acne is genetically occurring. Nonetheless, this condition may be associated with poor lifestyle choices such as smoking, poor diet, non active lifestyle, and many others.

Whilst bodybuilders are generally having a proper lifestyle, acne is mostly genetic and associated with the use of steroids. That’s similar to teenagers when they get a spike in testosterone and androgen levels and they are suffering from acne related issues.

Therefore, is the increase in the androgens that are going to trigger acne issues. And chances of this occurring are even higher in people who are genetically prone to get acne.

Isotretinoin Side Effects

Some of the most common Isotretinoin side effects are:

  • Dry lipsWhat-Is-Isotretinoin-man
  • Dry and fragile skin
  • Increased risks of sunburn

There are also rarer and uncommon side effects of Isotretinoin:

  • Muscle pains
  • Headaches
  • Behavior changes

There are also very rare but serious side effects too:

  • Depression
  • Visual changes
  • And even suicidal thoughts

The list of Isotretinoin is much longer, but they are all very unlikely to appear to a bodybuilder who needs much lower doses than a person fighting off with severe acne.

  • WARNING! Isotretinoin is very likely to cause developmental issues in the fetus even in very low dosages. Pregnant women shouldn’t use Isotretinoin.

Isotretinoin Dosages

Usually, Isotretinoin is given in doses of 50-150 mg a day to patients suffering from acne as a prescription drug by a doctor. Is usually recommended to use it with a large meal.

Nonetheless, bodybuilders who want to control acne during the cycle of steroids are generally using only 10-20 mg a day. Rarely in higher dosages. Usually, bodybuilders use it for 6-10 weeks.

But if the compound is prescribed by a doctor – use it exactly as was told by the doctor.

Keep in mind that the lower the dosage – the lower chances of side effects. Even if they do occur – lower chances usually mean milder side effects too. That’s why it is highly recommended to stay at the lowest effective dosage.


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Finasteride 1mg

Finasteride – the main active substance in the brand Propecia or Proscar, is an orally active drug that is proven helpful for treating and even preventing androgenic alopecia – male pattern baldness.

Most commonly, Finasteride is used alongside Minoxidil (an Over The Counter medication). That’s since these 2 are the only science-proven drugs to actually help users to maintain their hair. But in fact, in some cases, it was proven that Finasteride is helpful in some cases to actually regrow the hair in some areas of the scalp.

However, if you have been doing some research online, you may have noticed that Finasteride products are coming in 2 different strength versions. That’s Finasteride 1mg tablets and Finasteride 5mg tablets. Depending on the strength, sold as different brands, for different needs.


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Despite the fact that these 2 brands (and different strengths) contain the exact same active ingredient, they are actually designed for helping users with different purposes. Below, you are going to find what’s the difference between Finasteride 1mg and 5mg tablets. Depending on what exactly you’re searching for – you would decide which option is most suitable for you.

Finasteride 1mg in Bodybuilding

Considering you’re reading this article on this site, you’re most likely searching for Finasteride to save your hair during the use of anabolic steroids. You may have noticed that obtaining Finasteride is problematic as you need a prescription for it.

  • Luckily, on KalpaPharmaceuticals.to you can find Finasteride 1mg. And we do not ask for a prescription. All whilst making sure you get the best quality product for the cheapest possible price on the market.

Also, since you want to save your hair with Finasteride during the use of steroids, then you are most likely going to need Finasteride 1mg tablets. The administration is 1 tablet per day (Finasteride 1mg per day) for as long as you run steroids.


If you need Finasteride for a medical purpose – better talk to a doctor.

Valuable Info About Finasteride

Finasteride is a medication categorized as a 5alpha reductase inhibitor. The compound is working for hair loss by reducing androgenic activity in the scalp and it does so by lowering DHT levels in the body. The drug is inhibiting the enzyme 5a-reductase. This enzyme is responsible for converting testosterone into dihydrotestosterone (DHT).

Dihydrotestosterone is the main reason why men get male pattern hair loss. Those men who are genetically prone to high levels and/or being sensitive to DHT – are most likely going to lose their hair.

Finasteride is blocking DHT production. It lowers serum DHT levels in the body by up to 70% and in the prostate by up to 90%. That’s why Finasteride is also prescribed for Benign Prostatic Hyperplasia (enlargement of the prostate). DHT is also known for enlarging men’s prostate.

Finasteride 1mg

When talking specifically about Finasteride 1mg tablets, we’re actually talking about the original Propecia tablets (although can be found as other brands). This was the first brand and first medication approved for hair loss purposes.

So, Finasteride 1mg is used for hair loss purposes and is used on a daily basis. Usually for as long as the doctor decides is required. Or as said earlier, if used for saving hair during use of steroids, for as long as steroids are used.

Anabolic steroid users are at higher risk to lose hair. Is because all steroids speed up hair loss processes taken into consideration that they all increase DHT levels. Some do it to a greater extent than others.

When using Finasteride 1mg for hair loss – there’s no need to increase the dosage. Doing so, won’t offer any further benefits for hair loss, but increases the risks of side effects.


Finasteride 5mg

People who are suffering from Benign Prostatic Hyperplasia (BPH) are likely to be prescribed Finasteride too. But they are going to get this medication prescribed in 5mg tablets, as that is the daily dosage they should use for this compound.

Finasteride5mg is sold under the brand name Proscar, is intended specifically for the purpose of BPH treatment. It is a too high dosage for the purpose of hair loss prevention or treatment. That’s because, as was mentioned – it won’t offer any further benefits compared to 1 mg a day.



Despite the fact that tablets of Finasteride 1mg and 5mg contain the exact same active substance – they are prescribed for different purposes.

Most commonly, Finasteride 1mg tablets are sold as brand Propecia and Finasteride 5mg tablets are sold as brand Proscar – they are the first brands but can be found being sold as other brands as well.

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If you want to use Finasteride for hair loss, then we recommend you to administer Finasteride 1mg a day. Although side effects in men are uncommon, the drug still may offer some bad and long lasting side effects.

Letrozole For Gynecomastia


Letrozole which is the main active substance in the brand Femara (sold as numerous other brands) is an extremely popular and perhaps the most effective compound for treating gynecomastia. That’s why, Letrozole for gynecomastia is a very popular option and in case you’re predisposed to get this condition – having some Femara (Letrozole) handy is going to be a very good idea.

What is Letrozole?


Letrozole is an orally active medication that was created for the purpose of lowering estrogen levels and gynecomastia appears as a result of too much estrogen. Nonetheless, Letrozole was made for treating breast cancer in women – hormonally positive breast cancer.

That’s why Letrozole (Femara) in medical settings is mostly used for breast cancer treatment. But the compound is also used by anabolic steroid users (those who use aromatized steroids which convert into estrogen) to deal with estrogen related issues.

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Letrozole is an orally active Anti Estrogen and more specifically – an aromatase inhibitor (AI) that binds to aromatase enzymes preventing estrogen from being reduced. Thus, entire estrogen levels floating in the body are reduced.

What is Gynecomastia?

Gynecomastia (which is also known as man boobs, bitch tits, gyno, or others) is a health condition and is often considered one of the ugliest ones. Very often being extremely embarrassing which may lead to psychological insecurities.

Letrozole is known to be perhaps the best product on the market which can deal with gynecomastia in terms of preventing or treating it.

Gynecomastia is actually an abnormal development of mammary glands (breast tissues) in males due to either high estrogen or prolactin levels (these are mostly considered female hormones). Women may notice their breasts are larger during their period because of a spike in estrogen levels or they are larger when pregnant due to a spike in prolactin levels.

How Men Get Gynecomastia?

In men, most commonly, gynecomastia appears as a result of too much estrogen and sometimes as a result of high prolactin levels.

Too high levels of these “female” hormones occur in men due to various factors. It can be pubertal which leads to hormonal imbalances, poor lifestyle choices leading to hormonal imbalances but also – the use of anabolic steroids might increase estrogen levels.

A good amount of steroids are converted into these female hormones when administered. Luckily, not all steroids convert into estrogen – they won’t cause gyno, but many of them do.

In order to be able to continue the administration of those steroids and stay away from gynecomastia or treat gynecomastia if it appeared – you should add an Aromatase Inhibitor (AI) and Letrozole is one of the most effective AI out there.


Steroids Causing Gynecomastia

DHT (dihydrotestosterone) derived steroids are known to be safe for gynecomastia (like Oxandrolone, Drostanolone, Stanozolol, and others). Nonetheless, there’s Oxymetholone (Anadrol) that although is DHT derived – is binding to estrogen receptors. Therefore can cause estrogen related issues including gyno.

Trenbolone is a steroid that doesn’t convert into estrogen, but can increase prolactin levels. However, it is very rare for you to get gyno from Trenbolone because you’ve got to run it for a very long time.

Instead, all Testosterone based compounds convert into estrogen being very likely to cause gynecomastia including others so, steroids causing gyno include:

Symptoms of Gynecomastia

Of course, breasts won’t grow overnight, so you need to watch out for the early signs of gyno appearance. During the time you run aromatized steroids. Usually, such symptoms are sore breasts and sensitive nipples. If you do get these symptoms, you better add an aromatase inhibitor to your cycle.

How Letrozole Works For Gynecomastia?

As it was earlier mentioned – gynecomastia is appearing as a result of high female hormone levels (most commonly – estrogen). High estrogen levels may appear if you continue administering aromatized steroids for a long period of time or/ and in high doses.

But Letrozole is an Aromatase Inhibitor (AI) and the most powerful one. It inhibits aromatization and this leads to reduced levels of estrogen in the body. Without estrogen – gynecomastia can’t be formed.

Letrozole drops estrogen levels in women up to 98% and in men by 65%!

With this being said, you can stay away from gynecomastia very efficiently.


Letrozole Side Effects

Whilst trying to deal with estrogen related issues (like gyno), you may be administering too much Letrozole and that’s going to suppress estrogen levels too much. That’s a big problem because estrogen is a vital hormone.

Letrozole (Femara) should be used to keep normal estrogen levels, not to kill them. If you administer too much Letrozole, you are very likely to get low estrogen issues like:

  • Weakness
  • Fatigue
  • Dry / painful joints
  • Low sex drive
  • And others

Letrozole Dosage

When being prescribed to a health condition, it is generally offered at 2.5 mg per day. But that’s way too much for most bodybuilders.

Dosages are mostly ranged between 0.25 mg up to 1 mg per day or every other day. But dosages can be adjusted to everyone’s needs.


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What Does Nolvadex Do?


Nolvadex is the brand name of the drug called Tamoxifen Citrate and the brand is currently owned by AstraZeneca. But this product can be sold as numerous other brand names by numerous other pharmaceutical companies for much lower prices.

The compound is a Selective Estrogen Receptor Modulator (SERM) that is coming in the form of oral pills.

This is a very popular product that is widely used both in medical settings and in the bodybuilding world.


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Nolvadex in Medical Settings

Tamoxifen (Nolvadex) is FDA approved and is currently on the list of the World Health Organization (WHO) of essential medicines. This means that the compound is very effective and remains safe when used properly.

In medical settings, Nolvadex is used for the treatment or prevention of breast cancer in women and is used for the treatment of breast cancer or gynecomastia in men. Plus to that, Tamoxifen can be used for treating female infertility because there are studies proving that the compound is doubling the chances of pregnancy.

There are many other uses of Tamoxifen Citrate (Nolvadex) in medical settings too.

Nolvadex in Bodybuilding

The product Nolvadex in bodybuilding is very widely used. Because it is extremely helpful either for treating or preventing gynecomastia or for Post Cycle Therapy (PCT) plans.

However, Tamoxifen is not very effective for other estrogen related issues except for gynecomastia.

  • That’s why Aromatase Inhibitors (AIs) are preferred for gynecomastia prevention during the use of aromatized anabolic steroids.
  • Tamoxifen is preferred for PCT regimens in order to help bodybuilders restart their natural production of testosterone.


SERMs vs AIs

As mentioned, Nolvadex is a SERM (exactly as ClomidClomiphene Citrate) and is preferred for PCT plans. But for controlling estrogen levels and therefore preventing gynecomastia and other estrogenic issues, AIs (Aromatase Inhibitors) are more favored.

Both SERMs and AIs are known to deal with estrogen related issues (therefore are anti-estrogens).

However, AIs are known to bind to aromatase enzymes and therefore prevent aromatization. That’s why they lower the amount of estrogen in the body.

On the other hand, SERMs are binding to estrogen receptors and only to some specific estrogen receptors in the body (that’s why are called selective). Whilst they prevent the action of estrogen in some areas of the body, they are boosting the estrogen activity in other areas of the body.

How Does Nolvadex Work?

For example, it blocks estrogen action in breast tissues. That’s why they are helpful for preventing and treating breast cancer or gynecomastia.

Other than that, it also blocks the estrogen from reaching the pituitary gland. That’s why is helpful for producing testosterone naturally.

But it increases estrogen activity in ovaries. That’s why they are helpful for infertility issues.

That’s why, if you’re wondering what does Nolvadex do – you got the answer.

In short, it blocks the estrogen activity in some specific areas of the body and boosts estrogen activity in other areas of the body.


  • That’s why Nolvadex is lowering the chances of gynecomastia or estrogen receptor positive breast cancer and is helpful to boost the natural production of testosterone. It blocks estrogen from reaching the pituitary gland and breast tissues.

That’s why is so popular for bodybuilders and athletes running anabolic steroids who are likely to increase estrogen. This is a hormone that may cause gynecomastia from the use of aromatized steroids. Also, using steroids they are going to suppress the natural production of testosterone. All steroids suppress the production of testosterone.

Nolvadex Side Effects

Keep in mind that because of what Nolvadex does, you are likely to get side effects too. Usually, those men who run it properly do not get side effects. But this SERM is still not completely side effects free.

Tamoxifen is likely to cause nausea, vomiting, headaches as well as other serious side effects, but they usually occur only if you’re using the compound in way too high doses.

Nolvadex Doses

If you run Nolvadex for PCT then it usually starts at 40 mg per day for the first and second week. Then the dosage is lowered to 10-20 mg per day for the third and fourth week.

In case you’re using Nolvadex for gynecomastia then the dosages are highly dependent on various factors such as the dosage of steroids, whether you want to prevent gynecomastia or treat it etc. Generally, dosages are between 20 and 80 mg per day.


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Nolvadex is the brand name of the active substance Tamoxifen Citrate, however, the compound can be found as numerous other brand names and any brand with Tamoxifen Citrate is the same Nolvadex, just named differently.

This is an orally active medication that is FDA approved for the purpose of treating breast cancer in women and therefore, is an anti cancer drug. There are other uses of Nolvadex (Tamoxifen) in medical settings such as treating gynecomastia, infertility in women, and others.

What is Nolvadex?


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Tamoxifen Citrate is a Selective Estrogen Receptor Modulator (SERM) – the same family of drugs as Clomid (Clomiphene Citrate).

Therefore, this is an anti estrogen medication – the same as Aromatase Inhibitors (AIs). But SERMs and AIs are very different in their mechanism of action.

SERMs vs AIs

Whilst AIs are reducing total estrogen in the body by reducing the aromatization process (binding to aromatase enzymes), SERMs like Nolvadex are only blocking the action of estrogen (in some specific parts of the body) by binding to estrogen receptors.

Nolvadex in Bodybuilding

Nolvadex (Tamoxifen Citrate) is also very popular among bodybuilders who use anabolic steroids.

  • The compound has been discovered to be very effective at preventing or treating gynecomastia which is likely to appear when a male uses aromatized steroids.
  • However, this drug is mostly used by bodybuilders for their Post Cycle Therapy (PCT) protocols.

It is to recover back their natural testosterone production and normalize the hormonal balance. Both of which have to suffer when using steroids.

Nolvadex is mostly used for PCT plans because of its on-cycle needs – bodybuilders only benefit from gynecomastia prevention or treatment. But Tamoxifen can’t help with numerous other estrogen related issues.

That’s why AIs are mostly used during cycles with steroids, whilst SERMs for PCT.


Nolvadex Side Effects

When talking about the side effects of Nolvadex – it is important to mention that they greatly vary when the drug is used by women for their medical purposes and for men who use it for bodybuilding needs.

This is because women and men react differently to Nolvadex (Tamoxifen Citrate) but there are other factors at play such as men using it in lower doses and for shorter periods than women. That’s why men are much less likely to get side effects than women and they are more tolerable.

  • If men use Tamoxifen properly – side effects are very tolerable or they are not appearing at all. Some men report having boosted libido, others have it reduced. Sometimes they may feel emotional, rarely vomiting, headaches, or nausea or they could experience dry joints.

In the end, it is much less likely to get side effects from Nolvadex when used properly, compared to not having a PCT plan at all.

Nolvadex Dosage

Tamoxifen Citrate should be used carefully because although it has mild side effects – it is not completely side effects free. When Nolvadex is used for gynecomastia control during the use of steroids doses are ranged between 20-80 mg every day or every other day. It can be used for preventing or treating gynecomastia. Doses depend either on what you: to prevent or to treat, on your personal response as well as the amount of aromatized steroids you’re running.

  • Nolvadex PCT dosage is usually between 10-40 mg per day. The PCT plan starts when all anabolic steroids are flushed out of the system. The PCT plan lasts 3-8 weeks, most commonly 4 weeks.


Here’s one typical Nolvadex PCT plan: Week 1-2 = 40 mg per day; Week 3-4 = 20 mg per day.

Dosages and cycle lengths can and should be adjusted depending on various factors. For example personal response, anabolic steroid harshness, and various other factors.

Very often, Nolvadex is stacked with Clomid (Clomiphene Citrate) during the Post Cycle Therapy plan. This offers maximum effectiveness as they are both working in synergy together.



In the end, Tamoxifen Citrate (sold as Nolvadex or numerous other brands) is an extremely effective and popular medication. Is widely used both in medical settings and in the bodybuilding world. The compound can be obtained only by prescription.

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Tamoxifen For Men


Everyone dreams about packing on 50 pounds of lean muscle mass to their frame in a matter of months. We all know that you can do this by training very hard in the gym, eating the right amount of calories, getting a lot of sleep, and maybe adding a few supplements too. Nolvadex-Beligas

Nonetheless, whilst you must do all of this, you can’t reach your goals without anabolic steroids. That’s why there are so many people running steroids. But that’s why Tamoxifen for men is so popular too.

No, Tamoxifen is not a steroid – is an anti cancer oral medication classified as a Selective Estrogen Receptor Modulator (SERM). The same class of drugs as Clomiphene Citrate (Clomid).

With this being said, you may be wondering what Tamoxifen has to do with the use of steroids?

Any professional bodybuilder knows the answer.

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When you use anabolic steroids to increase muscle mass fast and efficiently, the body is going through hormonal imbalance. Steroids get your testosterone levels suppressed. That’s why you need Post Cycle Therapy (PCT) to recover from the use of anabolic steroids. So that’s where Tamoxifen is introduced. This is one of the most popular and most widely used drugs for PCT protocols (alongside Clomid).

  • Tamoxifen Citrate is mostly sold as brand Nolvadex (can be found as other brands) and is a popular SERM for PCT plans. Is often used alongside Clomid, but it can be used alone (or there are people going for Clomiphene alone). In the end, a combination of Nolvadex and Clomid is the most popular for PCT needs.

That’s the main reason why Tamoxifen for men is so popular and so important.

How Tamoxifen For Men Works?

In fact, when talking about the Tamoxifen mechanism of action – the compound is selectively binding to estrogen receptors in the body blocking their action. This is not an Aromatase Inhibitor stopping the aromatization and lowering total estrogen levels in the body.


Because of those certain estrogen receptors it binds to and blocks their action – Tamoxifen for men is helpful for 2 main purposes:

  1. Post Cycle Therapy for boosting testosterone levels and helping with recovery after steroid cycle
  2. For gynecomastia prevention or treatment during the use of anabolic steroid cycle


Tamoxifen For Men For PCT

In the first scenario, Tamoxifen Citrate (Nolvadex) is blocking estrogen from reaching the pituitary gland. By doing so, the pituitary keeps on releasing gonadotropins and this leads to a spike in Luteinizing Hormone (LH) and Follicle-Stimulating Hormone (FSH).

That’s how your body restarts the production of testosterone naturally. That’s why Tamoxifen for PCT is effective.

Tamoxifen For Men For Gyno

In the second scenario, Tamoxifen Citrate (Nolvadex) is blocking estrogen receptors in the breast tissues. That’s why it is helpful at treating and preventing breast cancer in men and women. Specifically, breast cancer that needs estrogen.

But Tamoxifen is also helpful at treating and preventing gynecomastia in men. In those men who either get naturally too high levels of estrogen or in men who run aromatized steroids. Those steroids that convert into estrogen in the body. Those men usually end up with high estrogen levels which leads to gynecomastia.

Important Notes About Tamoxifen

Men run Tamoxifen after the anabolic steroid cycle ends and all steroids are flushed out of the system for the PCT plan. For gynecomastia issues, Tamoxifen for men is run during the use of steroids.

  • NOTE! If Tamoxifen is prescribed to you for a health condition – run it exactly as is recommended by your doctor.

Is important to mention that because Tamoxifen is dealing with gynecomastia but is not very effective at dealing with other estrogen-related side effects during the use of aromatized steroids (like water retention, hypertension, etc.) – the compound is mostly used only for PCT plans. For gynecomastia issues, there are AIs that help both with gyno and with other estrogen related side effects.


Tamoxifen For Men Dosage

The dosage of Tamoxifen for men depends on various factors. It depends whether you run it for PCT or for gyno, it depends on your level of tolerance to the compound, the steroid cycle harshness as well as a number of other factors.

We recommend starting slowly on the compound and using the lowest effective dosage for you because although side effects of Nolvadex – Tamoxifen for men are a rare phenomenon – is still likely to occur.


As a reference – the dosage of Tamoxifen for men for PCT plans is between 40 mg and 10 mg per day.

With a PCT plan started after steroids are out of the system – like:

  • Week 1-2 Tamoxifen 40 mg a day
  • Week 3-4 Tamoxifen 20 mg a day.

Often people add Clomid 50 mg a day for the first 2 weeks and 25 mg a day for the last ones.

For gynecomastia, treatment doses might be higher. They range between 20 mg and 80 mg a day, as said, depending on various factors.

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Anastrozole VS Exemestane


Anastrozole vs Exemestane is a pretty popular topic taken into consideration that these are 2 extremely popular and widely used Aromatase Inhibitors (AIs), both coming in the form of oral pills and both offering similar results and even similar side effects.

  • PS: Another notable Aromatase Inhibitor (AI) is Letrozole with the brand name Femara.

Anastrozole is the chemical name in the brand Arimidex, yet it can be found as many other trade names too. The same applies to Exemestane which is the active substance in the most famous brand Aromasin. But there are many other trade names for it as well.

So, when you talk about Anastrozole vs Exemestane, the brands would be Arimidex vs Aromasin (many people might be more familiar with the brand of a compound instead of the chemical name).

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Anastrozole vs Exemestane Similarities

As it was earlier mentioned, both Anastrozole vs Exemestane (Arimidex vs Aromasin) come in form of oral pills. They are both Aromatase Inhibitors (AIs). Therefore they are both doing an amazing job in lowering total estrogen levels in the body as soon as they are administered.

They are even working similarly. Obviously offering similar results, similar side effects, and are used for similar needs.

Anastrozole and Exemestane are both binding to aromatase enzymes and therefore, preventing aromatization into estrogen, that’s how they lower estrogen levels in the body.

This is the reason why they are both used for similar needs – for whenever is required to lower estrogen levels.

For example, for medical purposes, they are used to lower estrogen levels in female patients suffering from breast cancer. Cancer that requires estrogen to form and grow. When estrogen is suppressed thanks to the use of either of these drugs, cancer cannot grow and it may be treated.

But in bodybuilding purposes, they are used either for PCT protocols (to boost testosterone levels) but that’s rare. Mostly Anastrozole and Exemestane are used for controlling estrogen during the use of aromatized steroids.


Aromasin vs Arimidex Uses

When users go for a steroid cycle, during the cycle – they are likely to get a spike in estrogen. Therefore, estrogen-related issues are possible.

When Arimidex or Aromasin are used – they control the estrogen.

Both are likely to offer similar side effects, taking into consideration that the most common side effects of these compounds are related to low estrogen levels (which is a sign that dosages are too high and too much estrogen is suppressed).

Some of the side effects can include:

  • Dry and painful joints
  • Fatigue and nausea
  • Low energy levels
  • Low mood and depression
  • No sex drive and libido
  • And there are others too

In the end, Anastrozole vs Exemestane are very similar compounds, yet there are still differences.

Anastrozole vs Exemestane Differences

Despite being so similar, they are still different.

  • The major difference between Arimidex and Aromasin (Anastrozole vs Exemestane) is that Arimidex (Anastrozole) is a nonsteroidal aromatase inhibitor unlike Aromasin (Exemestane) which is a steroidal AI (suicidal).

This means that as soon as Exemestane binds to aromatase enzymes, it permanently disables them. Unlike Anastrozole that only binds to the aromatase enzymes for as long as it is in the body. With this being said, Exemestane is better than Anastrozole at not allowing estrogen to rebound when you stop the administration.

Another benefit of Exemestane is that it lowers SHBG and whilst it won’t have a negative effect on gains like Anastrozole might – it may even be helpful for your gains. Due to this, it is also a better option for PCT plans.

However, Anastrozole has its own advantages over Exemestane.

For example, the first one is the fact that Arimidex is way cheaper than Exemestane. Many bodybuilders go for Arimidex instead of Aromasin mostly because they can save up a lot. In medical settings, Arimidex is the first-line treatment of breast cancer, but Aromasin is the second-line treatment.


Another thing that can be mentioned – is more likely you are going to get side effects from Exemestane rather than Anastrozole, is because Anastrozole is easier to control and adjust dosages. Mainly is because Exemestane permanently disables aromatization, unlike Anastrozole. Therefore it requires a while until estrogen levels come back to normal in case of emergency.

In Conclusion

  • Dosages of Anastrozole for bodybuilding: from 0.5 mg every other day up to 1 mg per day
  • Dosages of Exemestane for bodybuilding: from 12.5 mg every other day up to 25 mg per day

Arimidex-Beligas Supo-Aromasin-Beligas

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Aromasin is the brand name of the active substance Exemestane (any other brand with the same active substance is the same Aromasin, but sold under different trademarks) and this is an orally active medication that is medically used and FDA approved for treating breast cancer in women. If you’re familiar with Arimidex (Anastrozole) then you should know that Aromasin (Exemestane) is very similar to this compound and you can expect similar results.

There are some differences between the 2 drugs, yet final results would be pretty much the same.

Both Arimidex and Aromasin are classified as Aromatase Inhibitors (AIs) because they are both very effective at inhibiting the aromatization process in the body.


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The compound is used to lower total estrogen levels in body.

Therefore, in medical settings that helpful for women who suffers from estrogen receptor positive (ER+) breast cancer but in bodybuilding industry, is used during the use of anabolic steroids (aromatized steroids, also known as wet steroids) to prevent high estrogen levels and the related side effects.

Aromasin vs Arimidex

Taking into consideration that Arimidex is so popular, why would someone need Aromasin?

Well, AromasinExemestane is a suicidal aromatase inhibitor (AI) and that’s the main difference between Exemestane and Anastrozole. This means that unlike Anastrozole (which is a non-suicidal aromatase inhibitor) that only binds to aromatase enzymes when the drug is present in the body, Aromasin is permanently disabling the aromatase enzyme.

This offers Aromasin the great advantage of not allowing estrogen rebound that is possible to happen with other popular AIs such as Arimidex or Femara which temporarily stop estrogen from aromatizing.

At the same time, AromasinExemestane is more powerful than ArimidexAnastrozole.

  • This gives the advantage of better suppression of estrogen in emergency situations, but the disadvantage is that Anastrozole is easier to control in terms of side effects – plus is cheaper.
  • However, to make sure estrogen is suppressed and you won’t get estrogen rebound after the cycle, is worth the extra money for Aromasin.

Aromasin in Bodybuilding


Keep in mind that not all anabolic steroids aromatize (those that don’t are considered dry steroids – non aromatizable ones) .

But a lot of steroids do convert to estrogen and those are mostly bulking compounds that help you grow muscles, but using them requires adding an AI to prevent or treat high estrogen related issues that are possible to occur due to use of steroids.

If running these compounds without estrogenic protection, you are likely to get a spike in estrogen and this would offer different side effects. Some of the most common ones include: water retention, heart issues, high blood pressure, gynecomastia and others.

Aromasin Side Effects

If AromasinExemestane is used properly, side effects are almost unheard of among bodybuilders during the use of steroids. Remember the compound is used in order to combat the negative side effects, not to offer you new ones.

In the end, side effects are more likely to occur from use of steroids without AIs, than from the Aromasin when used properly.


If you get side effects from Aromasin (Exemestane) it means that you most likely use too much and dosages should be reduced.

  • NOTE! Females needing Aromasin for breast cancer are more likely to get side effects than bodybuilders for steroid cycles.

Too high dosages eliminates too much estrogen and this might lead to negative side effects such as dry out joints, low energy, mood and sex drive, inability to grow muscles and gain strength and others.

Aromasin Administration

As mentioned, this compound comes in the form of oral pills. The half life of Exemestane is around 25 hours, that’s why you can use tablets on a daily basis or even every other day.

Is recommended to start at a lower dose and then to increase only if needed, and increase according to your needs (due to reasons above explained).

Aromasin dosage is highly dependent on the steroid dose.

Most men start at a dosage of 12.5 mg every other day. They may increase to 12.5 mg every day or 25 mg every other day if they don’t get enough estrogenic protection. Doses might be upped to 25 mg on a daily basis if required.

Is recommended to have blood work done to check your levels of estrogen and determine how exactly to run AromasinExemestane dosage.

Start slowly and increase slowly only if required. Stay at the absolute lowest effective dosage. If aromasin-exemestane-odin-pharma side effects start appearing – reduce the dosage.

Aromasin (Exemestane) is a compound that is offered only by prescription, nonetheless, if you need it for bodybuilding purposes, no doctor would write a prescription.

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Anastrozole is perhaps the most popular and widely used Aromatase Inhibitor (AI) in the bodybuilding industry. The first and most popular brand of this substance is Arimidex but it might be found as other brands too. There are other notable AIs that can be mentioned such as Letrozole (Femara) and Exemestane (Aromasin), yet Anastrozole (Arimidex) remains one of the most popular ones.


  • The compound is designed to lower estrogen levels in the body when administered by binding to aromatize enzymes and therefore blocking estrogen formation and therefore lowering already existing estrogen levels. Therefore, it was originally created to treat breast cancer in women, estrogen positive breast cancer.

However, bodybuilders have found a way to use Anastrozole (Arimidex) when using anabolic steroids. There are certain types of steroids that convert into estrogen and by using those steroids, you are at risk of developing high estrogen related health problems. By adding Anastrozole to the cycle, users can continue the use of steroids without those estrogen symptoms.

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Explaining Anastrozole

When a man is running anabolic steroids for physique and performance enhancement, it is important to keep estrogen levels within normal range. Steroids that are known to convert into estrogen and therefore offer high estrogen levels are mostly known as bulking steroids or “wet” steroids.

  • Those that can be mentioned include: all testosterone, nandrolone and boldenone esters, Dianabol (methandienone) and others. It is important to know that not all steroids convert into estrogen at the same rate. For example, methandienone converts into estrogen way more than boldenone. Therefore, you are more likely to develop estrogen related issues with Dbol than EQ.Anastrozole-body-man

When running these compounds (especially in high doses and / or especially combined and / or especially for long periods) and not getting estrogen controlled – you are very likely to get estrogen related issues.

Some of the most well known estrogen symptoms are:

  • Gynecomastia (development of breast tissue)
  • Water retention or bloating offering “watery look of muscles”
  • High blood pressure (hypertension)
  • Can have a negative effect on your cardiovascular system
  • High estrogen may affect your libido and erection
  • Loss of energy and stamina
  • Feeling irritated, moody or even depression
  • Insomnia (sleeplessness)
  • And various other symptoms

That’s why it is so important to add Anastrozole (Arimidex) to the “wet steroids” cycle. It would lower estrogen levels and therefore keep you away from such side effects.

However, at the same time, if you’re going to overdo Anastrozole (Arimidex) you’re at risk of developing low estrogen related issues.

You need to use the compound in an attempt to keep estrogen levels within normal range and definitely not to completely suppress estrogen.

Too low estrogen is also coming with symptoms that can be pretty bad, despite this hormone being considered by many the “female hormone”. Is still required of men for proper functioning.

Anastrozole Side Effects

As said, Anastrozole side effects are mostly related to low estrogen levels and this is a sign that you’re using too much of this compound. When Anastrozole is properly used, side effects are very rarely noticed by men.

That’s because men use lower doses than women and they run it for much shorter periods than women (whilst rarely any woman needs less than 1 mg a day, most men do not need such doses, or maximum 1 mg a day, plus women need it for years, but men for weeks).

In the end, inhibiting the estrogen too aggressively (running Anastrozole in too high doses) then possible side effects of Anastrozole (Arimidex) are related to low estrogen levels and therefore you may get:

  • loss of energy
  • low libido
  • erectile dysfunction (ED)
  • depression

There are other side effects too.

  • After all, it is important to know that estrogen helps you gain muscles and strength – without it, you won’t be reaching your goals either.

Anastrozole can also offer side effects like nausea, vomiting, joint issues, hot flashes, insomnia, headaches and others.


Anastrozole Dosage and Administration

Arimidex (Anastrozole) comes in the form of oral pills and it has a half life of about 48 hours. The compound is slowly building up in your system. You can use it on a daily basis or every other day.

Most people start at 0.5 mg every other day, increase to 1 mg every other day or 1 mg a day. Rarely someone needs more or less than this dosage, but if you do, you can adjust it according to your needs.

The dosage of Anastrozole during anabolic steroid cycle is mostly depending on the steroid dosage but also on your personal response to the compounds and your overall estrogen levels (that’s why it is recommended to often have blood tests done).

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Clomiphene Citrate Uses


Clomid is by far the most famous brand name of Clomiphene Citrate but it can be found as other brand names too. Clomiphene Citrate has a lot of different uses but is considered one of the most popular medicines in the world of bodybuilding for those people who are running anabolic and androgenic steroids (AAS) for physique and performance improvement.

Clomiphene Citrate (Clomid) is actually a powerful anti-estrogen – is in the same category of drugs as Tamoxifen Citrate (Nolvadex) because both these compounds are SERMs – Selective Estrogen Receptor Modulators.


This medicine started to become very popular around in the 1970s as a very helpful compound for treating female infertility. Nowadays, Clomiphene Citrate uses of treating female infertility remain the most popular one in medical settings.

  • But in bodybuilding, Clomid is used by anabolic steroid users either during the cycle of steroids to deal with estrogen related side effects that can be caused by use of steroids, or to recover back the natural hormonal balance after the cycle with anabolic steroids, as a Post Cycle Therapy (PCT) drug.

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There are other Clomiphene Citrate uses too as it can be offered off label to men suffering from infertility too (because it is believed Clomid can boost sperm count) or as an alternative of Hormone Replacement Therapy (HRT) as it can boost testosterone levels. There are others Clomiphene Citrate uses too, but these are by far the most popular and widely used ones.


Clomiphene Citrate Uses For Infertility

Clomiphene (Clomid) is helpful since it boosts the levels of gonadotropin hormones in the blood. These are very important hormones for regulating the function of the sexual glands as they are controlling the levels of testosterone and estrogen. As much as we know – these are very important hormones for development and functioning of the male and female genitals, secondary sexual characteristics including many others.

Clomiphene Citrate is very helpful for a woman because it increases levels of gonadotropins and therefore, the egg is released (increases ovulation chances) and alongside increased ovulation chances, increases chances of getting pregnant.

Clomiphene Citrate Uses For Estrogen Protection On Cycle

Clomid (Clomiphene Citrate) is considered a powerful SERM and therefore a good anti-estrogenic compound. Since it has anti-estrogenic properties, bodybuilders and athletes running steroids are benefiting from using the compound because steroids derived from testosterone are converted into estrogens and when there are too many estrogens, side effects appear.

Clomid is used to deal with those estrogen related side effects during the cycle.

Some estrogen related side effects can be gynecomastia, increased blood pressure as a result of excessive fluid retention in the body caused by too much estrogen and many others.

However, professionals discovered that Clomiphene is a weak anti-gynecomastia compound and generally, aromatase inhibitors are doing a much better job at dealing with the synthesis of estrogen during the cycle. That’s why AIs are more effective than Clomid during the cycle.

That’s why, Clomid’s most popular use among steroid users is:

Clomiphene Citrate Uses For PCT Protocols

Post Cycle Therapy (PCT) is extremely important for every athlete who stops the anabolic steroid cycle and that’s because after each cycle with steroids, the hormonal balance is… unbalanced to say the least.

When you stop running the steroids, the natural synthesis of testosterone and natural hormonal balance starts to gradually recover back, but a full recovery is taking way too much time – starting from a few months up to a year or even longer.


  • PCT is there to help you speed up this entire process and Clomiphene Citrate (Clomid) is one of the best medicines out there for such needs. There is also Nolvadex (Tamoxifen Citrate) that is often used in combination with Clomiphene Citrate for the same purpose – Post Cycle Therapy as they are working in synergy.

There are other PCT compounds either, but these 2 are by far the most popular ones.

Clomiphene Citrate for PCT works the same way as for any other needs – blocking estrogen. It blocks it at the pituitary gland and that’s what leads to more gonadotropins released. More gonadotropins results in more testosterone. The anabolic steroid user is capable of maintaining gains after a cycle and to feel fine by avoiding the crash of testosterone.


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Regardless what’s your purpose of requiring Clomiphene Citrate (Clomid), you can buy the best quality product of the lowest prices online directly on KalpaPharmaceuticals.to You may also get Tamoxifen Citrate (Nolvadex) if you need for a good PCT plan as well as any other anabolic steroid for sale.


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